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Faculty and Staff
LIU Changning
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XTBG, Menglun, Mengla, 666303, Yunnan, China


  Changning Liu, Ph.D. 

  Investigator, Head of Bioinformatics Research Group, 

  Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences 

  Email: liuchangning@xtbg.ac.cn    Mobile: 86-151-9873-0541   


  Ph.D. 2002 – 2007      Bioinformatics, Institute of Computing Technology, CAS.  

  Advisors: Guojie Li and Runsheng Chen 

  B.S. 1996 – 2000        Molecular and Cell Biology, Wuhan University.  

  Advisor: Shijian Huang 

  Software Engineer Certificate (1998) Approved & issued by  

  Ministry of Information Industry, P.R.China. 



  2014 – present    Investigator, Xishuangbanna Tropical Botanical Garden, CAS 

  2010 – 2014        Associate Investigator, Institute of Computing Technology, CAS 

  2011.1 - 2013.1   Visiting Scholar, UT Dallas, Systems Biology Center 

  2007 – 2010        Assistant Investigator, Institute of Computing Technology, CAS 

  2002 – 2007        Research Assistant, Institute of Computing Technology, CAS 

  2006.7 - 2007.1   Visiting Student, Dept of Biostats and Comp Bio,  

  Dana-Farber Cancer Institute, Harvard School of Public Health 



  2011      Member of the Youth Innovation Promotion Association, CAS 

  2009      Member of the Best Research Laboratory of ICT, CAS 

  2008      Lu Jiaxi Young Scientist Award of CAS (K.C. Wong Education Foundation, HK) 

  2008      Member of the Best Research Team of ICT, CAS 

  2007      Enlisted Young Scientist for the ICT Hundred Talent Program 

  2007      Excellent Award of the CAS President's Scholarship 

  2007      Three Good Student of Chinese Academy of Sciences 

  2006      Special Award of the ICT Director's Scholarship 

  2006      Three Good Student Model of Chinese Academy of Sciences 

  2006      Three Good Student of Chinese Academy of Sciences 

  2003      Outstanding Graduate Scholarship of Graduate School of CAS 

  1999      Mathematics & Biology New Star Scholarship of Wuhan University 

  1997      Renmin Scholarship of Wuhan University 

  1996      Renmin Scholarship of Wuhan University 


  1.             Sun L, Luo HT, Liao Q, Bu DC, Zhao GG, Liu CN, Liu YN, Zhao Y: Systematic study of human long intergenic non-coding RNAs and their impact on cancer. Science China-Life Sciences 2013, 56(4):324-334. 

  2.             Li J, Xuan ZY, Liu CN: Long Non-Coding RNAs and Complex Human Diseases. Int J Mol Sci 2013, 14(9):18790-18808. 

  3.             Zhao GG, Bu DC, Liu CN, Li J, Yang J, Liu ZY, Zhao Y, Chen RS: CloudLCA: finding the lowest common ancestor in metagenome analysis using cloud computing. Protein & Cell 2012, 3(2):148-152. 

  4.             Bu DC, Yu KT, Sun SL, Xie CY, Skogerbo G, Miao RY, Xiao H, Liao Q, Luo HT, Zhao GG et al: NONCODE v3.0: integrative annotation of long noncoding RNAs. Nucleic Acids Research 2012, 40(D1):D210-D215. 

  5.             Yuan XY, Zhao Y, Liu CN, Bu DB: LEX-SVM: EXPLORING THE POTENTIAL OF EXON EXPRESSION PROFILING FOR DISEASE CLASSIFICATION. Journal of Bioinformatics and Computational Biology 2011, 9(2):299-316. 

  6.             Liao Q, Yuan XY, Xiao H, Liu CN, Lv ZY, Zhao Y, Wu ZD: Identifying Schistosoma japonicum Excretory/Secretory Proteins and Their Interactions with Host Immune System. PLoS One 2011, 6(8). 

  7.             Liao Q, Xiao H, Bu DC, Xie CY, Miao RY, Luo HT, Zhao GG, Yu KT, Zhao HT, Skogerbo G et al: ncFANs: a web server for functional annotation of long non-coding RNAs. Nucleic Acids Research 2011, 39:W118-W124. 

  8.             Liao Q, Liu CN, Yuan XY, Kang SL, Miao RY, Xiao H, Zhao GG, Luo HT, Bu DC, Zhao HT et al: Large-scale prediction of long non-coding RNA functions in a coding-non-coding gene co-expression network. Nucleic Acids Research 2011, 39(9):3864-3878. 

  9.             Yang Z, Ren F, Liu CN, He SM, Sun G, Gao QA, Yao L, Zhang YD, Miao RY, Cao Y et al: dbDEMC: a database of differentially expressed miRNAs in human cancers. BMC Genomics 2010, 11. 

  10.           Miao RY, Zhao HT, Yang HY, Mao YL, Lu X, Zhao Y, Liu CN, Zhong SX, Sang XT, Huang JF: Postoperative adjuvant antiviral therapy for hepatitis B/C virus-related hepatocellular carcinoma: A meta-analysis. World Journal of Gastroenterology 2010, 16(23):2931-2942. 

  11.           Liu CN, Li J, Zhao Y: Exploring hierarchical and overlapping modular structure in the yeast protein interaction network. BMC Genomics 2010, 11. 

  12.           Yuan XY, Liu CN, Yang PC, He SM, Liao Q, Kang SL, Zhao Y: Clustered microRNAs' coordination in regulating protein-protein interaction network. Bmc Systems Biology 2009, 3. 

  13.           Zhao Y, He SM, Liu CN, Ru SW, Zha HT, Yang Z, Yang PC, Yuan XY, Sun SW, Bu DB et al: MicroRNA regulation of messenger-like noncoding RNAs: a network of mutual microRNA control. Trends in Genetics 2008, 24(7):323-327. 

  14.           Sun SW, Yu CG, Qiao YT, Lin Y, Dong GJ, Liu CN, Zhang LF, Zhang Z, Cai JJ, Zhang H et al: Deriving the probabilities of water loss and ammonia loss for amino acids from tandem mass spectra. Journal of Proteome Research 2008, 7(1):202-208. 

  15.           He SM, Su H, Liu CN, Skogerbo G, He HS, He DD, Zhu XP, Liu T, Zhao Y, Chen RS: MicroRNA-encoding long non-coding RNAs. BMC Genomics 2008, 9. 

  16.           He SM, Liu CN, Skogerbo G, Zhao HT, Wang J, Liu T, Bai BY, Zhao Y, Chen RS: NONCODE v2.0: decoding the non-coding. Nucleic Acids Research 2008, 36:D170-D172. 

  17.           Yin YF, Zhao Y, Wang J, Liu CN, Chen SG, Chen RS, Zhao HT: antiCODE: a natural sense-antisense transcripts database. BMC Bioinformatics 2007, 8. 

  18.           Zhang ZH, Liu CN, Skogerbo G, Zhu XP, Lu HC, Chen L, Shi BC, Zhang Y, Wang J, Wu T et al: Dynamic changes in subgraph preference profiles of crucial transcription factors. Plos Computational Biology 2006, 2(5):383-391. 

  19.           Zhang Y, Sun SW, Wu T, Wang J, Liu CN, Chen L, Zhu XP, Zhao Y, Zhang ZH, Shi BC et al: Identifying Hfq-binding small RNA targets in Escherichia coli. Biochemical and Biophysical Research Communications 2006, 343(3):950-955. 

  20.           Wu T, Wang J, Liu CN, Zhang Y, Shi BC, Zhu XP, Zhang ZH, Skogerbo G, Chen L, Lu HC et al: NPInter: the noncoding RNAs and protein related biomacromolecules interaction database. Nucleic Acids Research 2006, 34:D150-D152. 

  21.           Wang XS, Zhao HT, Xu QW, Jin WB, Liu CN, Zhang HG, Huang ZB, Zhang XY, Zhang Y, Xin DQ et al: HPtaa database-potential target genes for clinical diagnosis and immunotherapy of human carcinoma. Nucleic Acids Research 2006, 34:D607-D612. 

  22.           Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, Buhay CJ, Chen R, Cree A, Ding Y et al: The DNA sequence, annotation and analysis of human chromosome 3. Nature 2006, 440(7088):1194-1198. 

  23.           Lu HC, Shi BC, Wu GW, Zhang Y, Zhu XP, Zhang ZH, Liu CN, Zhao Y, Wu T, Wang J et al: Integrated analysis of multiple data sources reveals modular structure of biological networks. Biochemical and Biophysical Research Communications 2006, 345(1):302-309. 

  24.           Deng W, Zhu XP, Skogerbo G, Zhao Y, Fu Z, Wang YD, He HS, Cai L, Sun H, Liu CN et al: Organization of the Caenorhabditis elegans small non-coding transcriptome: Genomic features, biogenesis, and expression. Genome Research 2006, 16(1):20-29. 

  25.           Liu CN, Bai BY, Skogerbo G, Cai L, Deng W, Zhang Y, Bu DB, Zhao Y, Chen RS: NONCODE: an integrated knowledge database of non-coding RNAs. Nucleic Acids Research 2005, 33:D112-D115.   


  PLoS One 

  BMC Genomics 

  Cell Proliferation 

  Journal of Theoretical Biology 

  BioMed Research International 

  International Journal of Biomedical Science 

  iConcept Transactions on Computational Intelligence in Bioinformatics 




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