Diterpenoids and phenanthrenones from the leaves and stems of Strophioblachia fimbricalyx
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作者: | Cheng L | ||||||||
刊物名称: | Tetrahedron Letters | ||||||||
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论文题目英文: | Diterpenoids and phenanthrenones from the leaves and stems of Strophioblachia fimbricalyx | ||||||||
年: | May 2016 | ||||||||
卷: | 57 | ||||||||
期: | 21 | ||||||||
页: | 2262–2265 | ||||||||
联系作者: | Xu YK | ||||||||
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影响因子: | 2.379 | ||||||||
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摘要: | Five new compounds, namely fimbricalyxoids A–D (1–4) and 13-O-methylfimbricalyx B (5), together with five known compounds (6–10) were isolated from the leaves and stems of Strophioblachia fimbricalyx. Fimbricalyxoid A (1), a cleistanthane diterpenoid, possesses a rare 3,20-oxybridge, while fimbricalyxoids C–D (3–4) are the first seco-ring-A pentanorditerpenoids. Their structures and absolute configuration were established based on NMR and MS data and ECD calculation (1). Compounds 1, 6, and 7 exhibited cytotoxicity against five human tumor cell lines with IC50 values in the range of 1.4–8.2 μM. | ||||||||
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