A new triterpenoid bearing octacosanoate from the stems and roots of Clerodendrum philippinum var. simplex (Verbenaceae)
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作者: | Yue JR | ||||||||
刊物名称: | Natural Product Research | ||||||||
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论文题目英文: | A new triterpenoid bearing octacosanoate from the stems and roots of Clerodendrum philippinum var. simplex (Verbenaceae) | ||||||||
年: | Mar 2015 | ||||||||
卷: | online | ||||||||
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联系作者: | Xu YK | ||||||||
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影响因子: | 1.225 | ||||||||
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摘要: | A new triterpenoid bearing octacosanoate, named taraxer-3b-yl octacosanoate (1), together with 13 known compounds (2–14), was isolated from the ethanol extract of the stems and roots of Clerodendrum philippinum var. simplex. The structure of taraxer-3b-yl octacosanoate (1) was elucidated by extensive spectroscopic analysis. Uncinatone (8) and clerodenone A (10) exhibited inhibition of lipopolysaccharideinduced nitric oxide production in RAW 264.7 macrophages with IC50 values of 12.50 and 3.18mM, respectively. | ||||||||
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