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Bamboo shoot fiber improves insulin sensitivity in high-fat diet-fed mice
| First Author: |
Li XF |
| Abstract: |
The aim of this study was to evaluate the role of bamboo shoot fiber (BSF) in regulating insulin sensitivity in mice. Two BSFs were obtained from D. hamiltonii and D. latiforus. C57BL/6 mice were fed a low-fat diet or a high-fat diet with 10% fiber as cellulose (HFC), or two BSFs (HFDH or HFDL) for 13？weeks. Compared with the HFC group, HFDH and HFDL groups exhibited considerably less body weight gain, lower levels of fasting glucose and insulin, and lower values of glucose areas under the curve during glucose and insulin tolerance tests. BSF groups also had lower glucoses stimulated insulin concentrations. In addition, more phosphorylation of Akt in insulin target tissues was associated with higher protein expression levels of PGC-1α and phosphorylated AMPK and p38 in BSF fed mice. These results indicated that BSF improved insulin sensitivity in high-fat diet-fed mice through enhancing insulin signaling and activating PGC-1α. |
| Contact the author: |
Zhang P |
| Page Number: |
510-517 |
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| Subject: |
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| Impact Factor: |
3.470 |
| Authors units: |
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| PubYear: |
Oct 2018 |
| Volume: |
49 |
| Publication Name: |
Journal of Functional Foods |
| The full text link: |
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| ISSN: |
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| Download: |
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